What Are Orthobiologics?

Our bodies are remarkable self-healers. When we injure a tendon, ligament, or joint, our body sends cells, proteins, and growth factors to repair the damage and calm inflammation. The trouble is, sometimes this natural response isn’t enough — especially with older injuries, arthritis, or the wear and tear of aging.

Orthobiologics are regenerative medicine therapies designed to boost this natural healing process, including PRP injections. Using materials like concentrated platelets, healing proteins, or tissue-derived cells, these therapies deliver a smart, targeted boost right where your body needs it most. The goal is not just to mask pain, but to actually help tissue repair, reduce inflammation, and slow down further damage.

Conditions Treated With Orthobiologics

Patients often ask, “What injuries or conditions can benefit from PRP injections or orthobiologic injections?” Here are the most common:

  • Knee osteoarthritis and cartilage wear
  • Shoulder pain and rotator cuff injuries
  • Tennis elbow and golfer’s elbow
  • Achilles tendinopathy and foot/ankle pain
  • Hip and knee labral tears
  • Post-surgical recovery support

These treatments are particularly effective for active adults who want to avoid or delay surgery while maintaining mobility and performance.

Orthobiologic Treatments: PRP, A2M, MFAT, and BMAC

Platelet-Rich Plasma (PRP): Healing From Within for Joint Pain Relief
One of the most widely used orthobiologic therapies is Platelet-Rich Plasma (PRP). This treatment draws a small amount of your blood, concentrates the platelets, and injects them directly into the injured area. Platelets are rich in natural growth factors that accelerate tissue repair, reduce inflammation, and calm pain. Because PRP comes from your own blood, it is very safe and avoids risks linked to medications or surgery.

Other Advanced Biologic Options

  • Alpha-2-Macroglobulin (A2M): A natural protein that binds and removes the enzymes that damage cartilage in arthritis. It can slow or stop the progression of joint degeneration.
  • MicroFat (MFAT): Derived from your own fat tissue, in mesenchymal stromal cells (MSCs, sometimes referred to as stem cells). MFAT is an orthobiologic therapy that provides both cushioning and biologic repair signals, reducing inflammation and supporting joint preservation.
  • Bone Marrow Aspirate Concentrate (BMAC): Collected from your bone marrow, which is also rich in MSCs and progenitor cells. BMAC combines these repair cells with healing proteins to aid regeneration in more advanced injuries or joint damage.

Stem-Cell–Rich Orthobiologic Therapies (MFAT & BMAC)

Mesenchymal stromal cells (MSCs) are multipotent cells found in both fat and bone marrow. While they don’t directly “turn into” new tissue, they release powerful anti-inflammatory and regenerative signals that help your body heal more effectively.

Orthobiologic therapies like MFAT and BMAC harness this MSC-rich environment to support recovery in ways traditional treatments cannot, making them some of the most promising biologic tools in modern sports medicine and orthopedic care.

Quick Comparison: Which Therapy Fits?

Treatment Best For Source Key Benefit
PRP (Platelet-Rich Plasma) Tendon injuries, mild arthritis Your blood Growth factors speed healing
A2M (Alpha-2-Macroglobulin) Moderate arthritis, inflammation Your blood Protects cartilage, reduces destructive enzymes
MFAT (MicroFat) Joint preservation, cartilage support Your fat tissue (abundant in MSCs) Cushioning + biologic repair signals from MSCs
BMAC (Bone Marrow Aspirate Concentrate) More advanced joint damage Your bone marrow (rich in MSCs) MSCs + proteins aid regeneration

Why Orthobiologics Are Different — and Better Than Standard Joint Pain Therapies

Compared to resting, medicating, or jumping straight to surgery, orthobiologics offer major advantages:

  • Faster Recovery: By targeting the root of the injury with natural healing agents, patients often see quicker improvements in strength and movement.
  • Less Downtime: Most treatments are performed in the office with small injections—far easier than surgery.
  • Joint Protection: They help repair tissue, slow degeneration, and may delay or prevent the need for joint replacement.
  • Personalized Care: Treatments are tailored to the injury, your activity level, and your long-term goals.

Recent studies have shown PRP can improve pain and function in patients with knee osteoarthritis compared to standard care, while A2M, MFAT, and BMAC continue to demonstrate protective and regenerative benefits in ongoing research.

How MOOV Combines Science and Care for Best Results

At MOOV Fort Lauderdale, orthobiologics are never a one-size-fits-all quick fix. We integrate these treatments into a comprehensive, physician-led recovery program designed to get you back to full activity:

  • A complete evaluation of your injury, lifestyle, and goals
  • Evidence-based biologic therapies (PRP, A2M, MFAT, BMAC)
  • Targeted physical therapy and movement retraining
  • Nutrition, sleep, and mental health optimization
  • Progress tracking with modern technology
  • Care led by board-certified physicians in Sports Medicine, Emergency Medicine, and Regenerative Medicine

Is Orthobiologic Treatment Right for You?

If you want to avoid or delay surgery, recover faster from a tendon or joint injury, or protect your long-term joint health, orthobiologics such as PRP and MFAT may be the answer.

A proper evaluation is essential — not every patient or injury is the same. The right biologic treatment should be chosen based on your specific condition, severity, and goals.

Looking Ahead: Smarter Healing for Lasting Performance

Orthobiologics represent the future of sports medicine and regenerative orthopedic care, offering joint preservation therapy and faster recovery. By combining biology-driven recovery with personalized treatment plans, we help patients not just get better, but come back stronger and more resilient.

Healing smarter means protecting your ability to stay active, competitive, and pain-free — now and well into the future.